Research use
For laboratory applications
Worldwide delivery
International shipping available
Technical information
Detailed specifications included
MCAM (CD146) Rabbit Polyclonal Antibody
Catalog:0992-0806-5
Available sizes
1 optionAvailability
Stock products usually ship within 24–48 hours. Non-stock products may require approximately 2–6 weeks.
Shipping conditions
No dry-ice requirement is indicated for this product.
Hazardous classification
This product is not currently marked as hazardous.
CD146 is a cell surface glycoprotein, originally identified as a melanoma antigen, whose expression is associated with tumor progression and the development of metastatic potential. Overexpression of CD146 in breast carcinoma cells results in a more cohesive cell growth and in the formation of smaller tumors in nude mice. During implantation and placentation, CD146 is expressed by the intermediate trophoblast in the placental site and binds to its putative receptor in uterine smooth muscle cells thus limiting trophoblastic invasion in the myometrium.
This product is intended for laboratory and research use only. Review the supplied documentation before use.
Product Name
MCAM (CD146) Rabbit Polyclonal Antibody
Catalog Number
0992-0806-5
Available Sizes
100 µL
Hazardous
No
Dry Ice
No
Host
Rabbit
Isotype
IgG
Species Reactivity
- Mouse
- Rat
Abbreviation
MCAM
Alternative Name
A32 antigen antibody CD 146 antibody CD146 antibody CD146 antigen antibody Cell surface glycoprotein MUC18 antibody Cell surface glycoprotein P1H12 antibody Gicerin antibody Mcam antibody Melanoma adhesion molecule antibody Melanoma associated antigen A32 antibody Melanoma associated antigen MUC18 antibody Melanoma associated glycoprotein MUC18 antibody Melanoma cell adhesion molecule antibody Melanoma-associated antigen A32 antibody Melanoma-associated antigen MUC18 antibody MelCAM antibody MUC 18 antibody MUC18 antibody MUC18_HUMAN antibody S endo 1 antibody S endo 1 endothelial associated antigen antibody S-endo 1 endothelial-associated antigen antibody
Applications
WB
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Cas
9007-83-4
Cellular Locus
Cell Membrane, nucleus.
Concentration
1 mg/mL
Conjugation
Non-conjugated
Dilution
WB: 1:500
Form
Liquid
Immunogen
Synthetic peptide within Human MCAM (CD146) aa 597-646 / 646.
Molecular Weight
Predicted band size: 72 kDa
Positive Control
Melanoma.
Purity
Immunogen affinity purified.
Recombinant Antibody
No
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Swiss Prot
P43121 Human
Type
Rabbit polyclonal Antibody