Research use
For laboratory applications
Worldwide delivery
International shipping available
Technical information
Detailed specifications included
CD133 Rabbit Polyclonal Antibody
Catalog:0992-0804-5
Available sizes
1 optionAvailability
Stock products usually ship within 24–48 hours. Non-stock products may require approximately 2–6 weeks.
Shipping conditions
No dry-ice requirement is indicated for this product.
Hazardous classification
This product is not currently marked as hazardous.
CD133 antigen, also known as prominin-1, is a glycoprotein that in humans is encoded by the PROM1 gene. It is a member of pentaspan transmembrane glycoproteins, which specifically localize to cellular protrusions. When embedded in the cell membrane, the membrane topology of prominin-1 is such that the N-terminus extends into the extracellular space and the C-terminus resides in the intracellular compartment. The protein consists of five transmembrane segments, with the first and second segments and the third and fourth segments connected by intracellular loops while the second and third as well as fourth and fifth transmembrane segments are connected by extracellular loops. While the precise function of CD133 remains unknown, it has been proposed that it acts as an organizer of cell membrane topology. CD133 is expressed in hematopoietic stem cells, endothelial progenitor cells, glioblastoma, neuronal and glial stem cells, various pediatric brain tumors, as well as adult kidney, mammary glands, trachea, salivary glands, uterus, placenta, digestive tract, testes, and some other cell types.
This product is intended for laboratory and research use only. Review the supplied documentation before use.
Product Name
CD133 Rabbit Polyclonal Antibody
Catalog Number
0992-0804-5
Available Sizes
100 µL
Hazardous
No
Dry Ice
No
Host
Rabbit
Isotype
IgG
Species Reactivity
- Human
- Mouse
- Rat
Abbreviation
Prominin-1 Antigen AC133 Prominin-like protein 1 CD133 PROM1
Alternative Name
AC133 antibody Antigen AC133 antibody CD133 antibody CORD12 antibody Hematopoietic stem cell antigen antibody hProminin antibody MCDR2 antibody MSTP061 antibody OTTHUMP00000217744 antibody OTTHUMP00000217745 antibody OTTHUMP00000217746 antibody PROM1 antibody PROM1_HUMAN antibody Prominin I antibody Prominin like 1 antibody Prominin like protein 1 precursor antibody Prominin mouse like 1 antibody Prominin-1 antibody Prominin-like protein 1 antibody Prominin1 antibody PROML1 antibody RP41 antibody STGD4 antibody
Applications
WB, FC
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Cas
9007-83-4
Cellular Locus
Cell membrane.
Concentration
1 mg/mL
Conjugation
Non-conjugated
Dilution
WB: 1:500 ;FC: 1:50-1:100
Form
Liquid
Immunogen
Synthetic peptide within human CD133 aa 800-865.
Molecular Weight
Predicted band size 97 kDa.
Positive Control
Human stomach tissue lysates, PC-12 cell lysates, F9.
Purity
Immunogen affinity purified.
Recombinant Antibody
No
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Swiss Prot
O43490 Human, O54990 Mouse
Type
Rabbit polyclonal Antibody