Research use
For laboratory applications
Worldwide delivery
International shipping available
Technical information
Detailed specifications included
Mouse 4-1BB Ligand / TNFSF9 Protein, Fc Tag
Catalog:0716-41L-M5257-1mg
Available sizes
1 optionAvailability
Stock products usually ship within 24–48 hours. Non-stock products may require approximately 2–6 weeks.
Shipping conditions
No dry-ice requirement is indicated for this product.
Hazardous classification
This product is not currently marked as hazardous.
Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD) . Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
This product is intended for laboratory and research use only. Review the supplied documentation before use.
Product Name
Mouse 4-1BB Ligand / TNFSF9 Protein, Fc Tag
Catalog Number
0716-41L-M5257-1mg
Available Sizes
1 mg
Hazardous
No
Dry Ice
No
Host
HEK293
Accession Number
NP_033430
Additives
Trehalose
Background
Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD) . Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
Bioactivity
Immobilized Mouse 4-1BB, His Tag (Cat. No. 41B-M52H7) at 0.5 μg/mL (100 μL/well) can bind Mouse 4‑1BB Ligand, Fc Tag (Cat. No. 41L-M5257) with a linear range of 0.4-6 ng/mL (QC tested).
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Conjugation
Unconjugated
Datasheet
https://console.acrobiosystems.com/public/product/pdf/ds/41L-M5257.pdf
Endotoxin
1.0 EU per μg
Expression Region
Arg 104 - Glu 309
Format
Powder
Molecular Weight
49.0 kDa
Package Size
200ug*5
Purity
95%
Shipping Conditions
RT
Source
Mouse
Species
Mouse
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 49.0 kDa. The protein migrates as 60-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Stability
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Storage Conditions
-20°C
Tag
C-Fc
Target
4-1BB Ligand
Additional Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Host Or Source
HEK293
Preservative
Trehalose
Protein Id
NP_033430